Anti-IL-1 alpha/IL1A Antibody
Boster Bio Anti-IL-1 alpha/IL1A Antibody catalog # A01144-3. Tested in WB, IHC, ICC, IF, ELISA applications. This antibody reacts with Human, Mouse.
Product Specifications
Background
Interleukin-1α (IL-1 alpha) is a protein that plays a crucial role in the regulation of a number of key cellular processes. IL-1 Alpha is a cytokine and a potent mediator of body's response to inflammation, microbial invasion, tissue injury and immunological response. In addition, recent studies suggest that IL-1 Alpha also has a role in wound healing, rheumatoid arthritis, Alzheimer's disease and tumor growth. IL-1 Alpha functions as an alarmin during the process of sterile inflammation. It serves as a signal from dying cells to potentiate the inflammatory response, increasing the expression of other secreted factors like IL-6 and IL-8. IL-1 Alpha was found to affect the cell cycle of osteosarcoma cell to reduce cell growth. IL-1 Alpha is initially translated as approximately 30-kD polypeptides that are processed to approximately 17.5-kD polypeptides prior to, or during, release from macrophages.
Synonyms
IL1A; IL 1 alpha; Hematopoietin-1; IL-1; IL1; IL1 ALPHA
Gene Name
IL1A
UniProt
P01583
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
E.coli-derived human IL-1 alpha/IL1A recombinant protein (Position: K3-N269) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
Interleukin 1 alpha
Protein Name
Interleukin-1 alpha
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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