Anti-CD40L CD40LG Antibody
Boster Bio Anti-CD40L CD40LG Antibody catalog # A01114. Tested in WB, ICC/IF, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
CD40 ligand; CD40-L; T-cell antigen Gp39; TNF-related activation protein; TRAP; Tumor necrosis factor ligand superfamily member 5; CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; CD40LG; CD40L, TNFSF5, TRAP
Gene Name
CD40LG
UniProt
P29965
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant protein
Clonality
Polyclonal
Tissue Specificity
Specifically expressed on activated CD4+ T- lymphocytes.
Applications
WB, ICC, IF, IHC, Flow Cytometry
Purification
ProA affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Cytokine that binds to CD40/TNFRSF5 (PubMed:1280226) . Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (PubMed:8617933) . Induces the activation of NF-kappa-B and kinases MAPK8 and PAK2 in T- cells. Induces tyrosine phosphorylation of isoform 3 of CD28 (PubMed:15067037) . Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching (By similarity) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
29274 MW
Gene Name Synonym
CD40 ligand
Subcellular Location
Cell membrane
Protein Name
CD40 ligand
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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