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Anti-STRADA Antibody (C-term)

Boster Bio Anti-STRADA Antibody (C-term) (Catalog # A01112-2) . Tested in WB, IHC-P, IF, Flow Cytometry application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Background

Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

Synonyms

STE20-related kinase adapter protein alpha, STRAD alpha, STE20-related adapter protein, Serologically defined breast cancer antigen NY-BR-96, STRADA, LYK5 {ECO:0000312|EMBL:AAP422801}, STRAD

Gene Name

STRADA

UniProt

Q7RTN6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This STRADA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 303-346 amino acids from the C-terminal region of human STRADA.

Clonality

Polyclonal

Applications

WB, IHC-P, IF, Flow Cytometry

Field of Research

Cancer, Cell Biology, Metabolism

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

48369 Da

Subcellular Location

Nucleus. Cytoplasm

Prediction Reactivity

Monkey

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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