Anti-STRADA Antibody (C-term)
Boster Bio Anti-STRADA Antibody (C-term) (Catalog # A01112-2) . Tested in WB, IHC-P, IF, Flow Cytometry application (s) . This antibody reacts with Human, Mouse.
Product Specifications
Background
Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.
Synonyms
STE20-related kinase adapter protein alpha, STRAD alpha, STE20-related adapter protein, Serologically defined breast cancer antigen NY-BR-96, STRADA, LYK5 {ECO:0000312|EMBL:AAP422801}, STRAD
Gene Name
STRADA
UniProt
Q7RTN6
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This STRADA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 303-346 amino acids from the C-terminal region of human STRADA.
Clonality
Polyclonal
Applications
WB, IHC-P, IF, Flow Cytometry
Field of Research
Cancer, Cell Biology, Metabolism
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
48369 Da
Subcellular Location
Nucleus. Cytoplasm
Prediction Reactivity
Monkey
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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