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Anti-DBH Antibody (N-term P42)

Boster Bio Anti-DBH Antibody (N-term P42) (Catalog # A01110-2) . Tested in WB, IF application (s) . This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. [provided by RefSeq].

Synonyms

Dopamine beta-hydroxylase, Dopamine beta-monooxygenase, Soluble dopamine beta-hydroxylase, DBH

Gene Name

DBH

UniProt

P09172

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This DBH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-56 amino acids from the N-terminal region of human DBH.

Clonality

Polyclonal

Applications

WB, IF

Field of Research

Cancer, Metabolism, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Catalyzes the hydroxylation of dopamine to noradrenaline (also known as norepinephrine), and is thus vital for regulation of these neurotransmitters.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

69065 Da

Subcellular Location

[Soluble dopamine beta-hydroxylase]: Cytoplasmic vesicle, secretory vesicle lumen Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen. Secreted

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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