Anti-ATP7A (H640) Antibody
Boster Bio Anti-ATP7A (H640) Antibody catalog # A01085. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Copper-transporting ATPase 1;3.6.3.54; Copper pump 1; Menkes disease-associated protein; ATP7A; MC1, MNK
Gene Name
ATP7A
UniProt
Q04656
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 620-670 of Human ATP7A.
Clonality
Polyclonal
Tissue Specificity
Found in most tissues except liver. Isoform 3 is widely expressed including in liver cell lines. Isoform 1 is expressed in fibroblasts, choriocarcinoma, colon carcinoma and neuroblastoma cell lines. Isoform 2 is expressed in fibroblasts, colon carcinoma and neuroblastoma cell lines.
Applications
IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
163373 MW
Applications Notes
IHC: 1:50-1:200
Gene Name Synonym
Copper-transporting ATPase 1
Subcellular Location
Golgi apparatus, trans-Golgi network membrane
Protein Name
Copper-transporting ATPase 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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