Anti-Caspase-7 (active/cleaved) Antibody
Boster Bio Anti-Caspase-7 (active/cleaved) Antibody (Catalog# A01044) . Tested in IP, IHC, WB application (s) . This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Caspase-7; CASP-7;3.4.22.60; Apoptotic protease Mch-3; CMH-1; ICE-like apoptotic protease 3; ICE-LAP3; Caspase-7 subunit p20; Caspase-7 subunit p11; CASP7; MCH3
Gene Name
CASP7
UniProt
P55210
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A recombinant catalytically active human Caspase-7 (active/cleaved) protein
Clonality
Polyclonal
Tissue Specificity
Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.
Applications
IP, IHC, WB
Field of Research
Apoptosis, Apoptotic Markers, Cancer, Caspases, Cell Biology, Cell Death, Intracellular, Invasion/Microenvironment, Metabolism, Metabolism Processes, Pathways and Processes, Proteolysis/Ubiquitin, Proteolytic Enzymes
Concentration
0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form
Liquid
Function
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs) . Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly- 217' bond. Overexpression promotes programmed cell death.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Observed Molecular Weight
34277 MW
Gene Name Synonym
Caspase-7
Subcellular Location
Cytoplasm.
Isotype
Rabbit IgG
Contents
50 μ l sera
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