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Anti-Caspase-7 (active/cleaved) Antibody

Boster Bio Anti-Caspase-7 (active/cleaved) Antibody (Catalog# A01044) . Tested in IP, IHC, WB application (s) . This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Caspase-7; CASP-7;3.4.22.60; Apoptotic protease Mch-3; CMH-1; ICE-like apoptotic protease 3; ICE-LAP3; Caspase-7 subunit p20; Caspase-7 subunit p11; CASP7; MCH3

Gene Name

CASP7

UniProt

P55210

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A recombinant catalytically active human Caspase-7 (active/cleaved) protein

Clonality

Polyclonal

Tissue Specificity

Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.

Applications

IP, IHC, WB

Field of Research

Apoptosis, Apoptotic Markers, Cancer, Caspases, Cell Biology, Cell Death, Intracellular, Invasion/Microenvironment, Metabolism, Metabolism Processes, Pathways and Processes, Proteolysis/Ubiquitin, Proteolytic Enzymes

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs) . Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly- 217' bond. Overexpression promotes programmed cell death.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Observed Molecular Weight

34277 MW

Gene Name Synonym

Caspase-7

Subcellular Location

Cytoplasm.

Isotype

Rabbit IgG

Contents

50 μ l sera

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