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Anti-PBX1 Antibody

Boster Bio Anti-PBX1 Antibody catalog # A01039-3. Tested in WB, ICC/IF, IP, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis and required for skeletal patterning and programming. A chromosomal translocation, t (1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name

PBX1

UniProt

P40424

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human PBX1 recombinant protein (Position: 3-346) .

Clonality

Polyclonal

Applications

WB, ICC/IF, IP, ELISA

Purification

Immunogen affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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