Anti-DNA replication factor Cdt1 CDT1 Antibody
Boster Bio Anti-DNA replication factor Cdt1 CDT1 Antibody catalog # A01035. Tested in WB, IHC, IP applications. This antibody reacts with Human.
Product Specifications
Synonyms
DNA replication factor Cdt1; Double parked homolog; DUP; CDT1
Gene Name
CDT1
UniProt
Q9H211
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein
Clonality
Polyclonal
Applications
WB, IHC, IP
Purification
ProA affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Required for both DNA replication and mitosis (PubMed:11125146, PubMed:22581055, PubMed:21856198, PubMed:14993212, PubMed:26842564) . DNA replication licensing factor, required for pre-replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC) (PubMed:14672932) . Required also for mitosis by promoting stable kinetochore-microtubule attachments (PubMed:22581055) . Potential oncogene (By similarity) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
60390 MW
Gene Name Synonym
DNA replication factor Cdt1
Subcellular Location
Nucleus
Protein Name
DNA replication factor Cdt1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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