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Anti-DNA pol lambda Antibody

Boster Bio Anti-DNA pol lambda Antibody catalog # A00959. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

DNA polymerase lambda ; Pol Lambda ;2.7.7.7

Gene Name

POLL

UniProt

Q9UGP5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human DNA Polymerase lambda. AA range:451-500

Clonality

Polyclonal

Tissue Specificity

Expressed in a number of tissues. Abundant in testis.

Applications

WB, IHC, IF, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

DNA polymerase that functions in several pathways of DNA repair (PubMed:11457865, PubMed:19806195, PubMed:20693240) . Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA (PubMed:11457865, PubMed:19806195) . Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination (PubMed:19806195, PubMed:20693240) . Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities (PubMed:10982892, PubMed:10887191, PubMed:12809503, PubMed:14627824, PubMed:15537631, PubMed:19806195) . Has also a 5'-deoxyribose-5- phosphate lyase (dRP lyase) activity (PubMed:11457865, PubMed:19806195) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

63482 MW

Gene Name Synonym

DNA polymerase lambda

Subcellular Location

Nucleus

Protein Name

DNA polymerase lambda

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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