Anti-TOP2A (phospho-S1106) Antibody
Boster Bio Anti-TOP2A (phospho-S1106) Antibody catalog # A00953S1106. Tested in WB applications. This antibody reacts with Human, Rat, Mouse.
Product Specifications
Synonyms
DNA topoisomerase 2-alpha;5.99.1.3; DNA topoisomerase II, alpha isozyme; TOP2A; TOP2
Gene Name
TOP2A
UniProt
P11388
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic phosphopeptide derived from human TOP2A around the phosphorylation site of Serine1106.
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
174385 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
DNA topoisomerase 2-alpha
Subcellular Location
Cytoplasm
Protein Name
DNA topoisomerase 2-alpha
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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