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Anti-c-PLA2 (N499) PLA2G4A Antibody

Boster Bio Anti-c-PLA2 (N499) PLA2G4A Antibody catalog # A00854. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Cytosolic phospholipase A2; cPLA2; Phospholipase A2 group IVA; Phospholipase A2;3.1.1.4; Phosphatidylcholine 2-acylhydrolase; Lysophospholipase;3.1.1.5; PLA2G4A; CPLA2, PLA2G4

Gene Name

PLA2G4A

UniProt

P47712

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 480-530 of Human c-PLA2.

Clonality

Polyclonal

Tissue Specificity

Expressed in various tissues such as macrophages, platelets, neutrophils, fibroblasts and lung endothelium.

Applications

WB, IHC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

85239 MW

Gene Name Synonym

Cytosolic phospholipase A2

Subcellular Location

Cytoplasm. Cytoplasmic vesicle. Translocates to membrane vesicles in a calcium-dependent fashion.

Protein Name

Cytosolic phospholipase A2

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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