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Anti-eIF4B (phospho-Ser422) Antibody

Boster Bio Anti-eIF4B (phospho-Ser422) Antibody catalog # A00846S422. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Eukaryotic translation initiation factor 4B; eIF-4B; EIF4B

Gene Name

EIF4B

UniProt

P23588

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic phosphopeptide derived from human eIF4B around the phosphorylation site of Serine 422.

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'- terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

69151 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Eukaryotic translation initiation factor 4B

Protein Name

Eukaryotic translation initiation factor 4B

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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