Anti-IRS2 Antibody (C-term)
Boster Bio Anti-IRS2 Antibody (C-term) (Catalog # A00805-1) . Tested in WB, IF, IHC-P application (s) . This antibody reacts with Human.
Product Specifications
Background
Insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. This protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Synonyms
Insulin receptor substrate 2, IRS-2, IRS2
Gene Name
IRS2
UniProt
Q9Y4H2
Host
Rabbit
Reactivity
Human
Immunogen
This IRS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1309-1338 amino acids from the C-terminal region of human IRS2.
Clonality
Polyclonal
Applications
WB, IF, IHC-P
Field of Research
Cardiovascular, Metabolism, Signal Transduction, Interleukins
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
May mediate the control of various cellular processes by insulin.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
137334 Da
Subcellular Location
Cytoplasm, cytosol.
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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