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Anti-IRS2 Antibody (C-term)

Boster Bio Anti-IRS2 Antibody (C-term) (Catalog # A00805-1) . Tested in WB, IF, IHC-P application (s) . This antibody reacts with Human.

Product Specifications

Background

Insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. This protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.

Synonyms

Insulin receptor substrate 2, IRS-2, IRS2

Gene Name

IRS2

UniProt

Q9Y4H2

Host

Rabbit

Reactivity

Human

Immunogen

This IRS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1309-1338 amino acids from the C-terminal region of human IRS2.

Clonality

Polyclonal

Applications

WB, IF, IHC-P

Field of Research

Cardiovascular, Metabolism, Signal Transduction, Interleukins

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Function

May mediate the control of various cellular processes by insulin.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

137334 Da

Subcellular Location

Cytoplasm, cytosol.

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Curated Selection

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