Anti-DNA repair protein XRCC4 XRCC4 Antibody
Boster Bio Anti-DNA repair protein XRCC4 XRCC4 Antibody catalog # A00787. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
DNA repair protein XRCC4; X-ray repair cross-complementing protein 4; XRCC4
Gene Name
XRCC4
UniProt
Q13426
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthetic peptide corresponding to residues in Human XRCC4.
Clonality
Polyclonal
Tissue Specificity
Widely expressed.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V (D) J recombination. Binds to DNA and to DNA ligase IV (LIG4) . The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
38287 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
DNA repair protein XRCC4
Subcellular Location
Nucleus
Protein Name
DNA repair protein XRCC4
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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