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Anti-ACE2 Antibody

Boster Bio Anti-ACE2 Antibody (Catalog # A00756) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

COVID-19 (2019-nCoV) may use ACE2 as a receptor in humans

Synonyms

ACEH, Angiotensin-converting enzyme 2, ACE-related carboxypeptidase, ACEH, SARS-CoV receptor, SARS-CoV-2 receptor

Gene Name

ACE2

UniProt

Q9BYF1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

Anti-ACE2 has no cross response to ACE1.

Immunogen

Anti-ACE2 antibody was raised against a peptide corresponding to 17 amino acids near the center of human ACE2. The immunogen is located within amino acids 180 - 230 of ACE2.

Clonality

Polyclonal

Tissue Specificity

Expressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells. Expressed in lung alveolar epithelial cells, enterocytes of the small intestine, Leydig cells and Sertoli cells (at protein level) . Expressed in heart, kidney, testis, and gastrointestinal system.

Applications

ELISA, WB, IHC-P, IF

Field of Research

Infectious Diseases

Purification

ACE2 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin- 13 and dynorphin-13 with high efficiency. May be an important regulator of heart function.

Storage Conditions

ACE2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Observed Molecular Weight

92463 MW

Gene Name Synonym

Angiotensin I converting enzyme (peptidyl-dipeptidase A) 2

Subcellular Location

Processed angiotensin-converting enzyme 2: Secreted.

Prediction Reactivity

Bovine

Protein Name

Angiotensin I converting enzyme (peptidyl-dipeptidase A) 2

Isotype

IgG

Contents

ACE2 Antibody is supplied in PBS containing 0.02% sodium azide.

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