Anti-MTM1 Antibody
Boster Bio Anti-MTM1 Antibody catalog # A00749-2. Tested in WB, IHC, ICC/IF, ELISA. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
The MTM1 (Myotubularin) gene encodes a protein that belongs to a family of putative tyrosine phosphatases. It is required for muscle cell differentiation. The protein is also a potent phosphatidylinositol 3-phosphate (PI3P) phosphatase, which is a 66 kDa ubiquitous protein that is found mutated in the X-linked genetic disorder myotubular myopathy (XLMTM) .MTM1 could therefore act as a regulator of the highly active phosphoinositide (PI) metabolism in cells, where interconversions of the eight PIs described so far is controlled by a set of specific kinases and phosphatases (PMID:14660569) . MTM1 has two isoforms with the molecular mass of 66kDa and 70 kDa.
Gene Name
MTM1
UniProt
Q13496
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human MTM1 recombinant protein (Position: S3-Q359) .
Clonality
Polyclonal
Applications
WB, IHC, ICC/IF, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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