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Anti-Cyclin B1 CCNB1 Antibody

Boster Bio Anti-Cyclin B1 CCNB1 Antibody (Catalog # A00745) . Tested in IHC, WB applications. This antibody reacts with Human.

Product Specifications

Background

The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product forms a complex with p34 (cdc2) to form the maturation-promoting factor (MPF) . Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.

Synonyms

Cyclin B1, G2/mitotic-specific cyclin-B1

Gene Name

CCNB1

UniProt

P14635

Host

Rabbit

Reactivity

Human

Immunogen

Anti-Cyclin B1 antibody was produced by repeated immunizations of full length fusion protein corresponding to the human gene.

Clonality

Polyclonal

Applications

ELISA, IHC, IP, WB

Purification

This product was prepared from monospecific antiserum by delipidation and defibrination. Antiserum will specifically react with a 55-62 kDa Cyclin B1 protein from human, rat and mouse tissue. No reaction was observed against other related cyclins. Cross-reactivity with Cyclin B1 from other species may also occur.

Concentration

80 mg/mL by Refractometry

Form

Liquid (sterile filtered)

Function

Essential for the control of the cell cycle at the G2/M (mitosis) transition.

Shipping Conditions

Dry Ice Shipping

Storage Conditions

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

Observed Molecular Weight

48337 MW

Gene Name Synonym

G2/mitotic-specific cyclin-B1

Subcellular Location

Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Isotype

Antiserum

Contents

0.01% (w/v) Sodium Azide

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