Anti-SSB (T362) Antibody
Boster Bio Anti-SSB (T362) Antibody catalog # A00705T362. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Lupus La protein; La autoantigen; La ribonucleoprotein; Sjoegren syndrome type B antigen; SS-B; SSB
Gene Name
SSB
UniProt
P05455
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 331-380 of Human SSB.
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 110% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Binds to the 3' poly (U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation (PubMed:3192525, PubMed:2470590) . In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:12384597) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
46837 MW
Applications Notes
WB: 1:1000-1:2000
Gene Name Synonym
Lupus La protein
Subcellular Location
Nucleus .
Protein Name
Lupus La protein
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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