Anti-SSB (phospho-S366) Antibody
Boster Bio Anti-SSB (phospho-S366) Antibody catalog # A00705S366. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Lupus La protein; La autoantigen; La ribonucleoprotein; Sjoegren syndrome type B antigen; SS-B; SSB
Gene Name
SSB
UniProt
P05455
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic phosphopeptide derived from human SSB around the phosphorylation site of Serine 366.
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 110% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Binds to the 3' poly (U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation (PubMed:3192525, PubMed:2470590) . In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:12384597) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
46837 MW
Applications Notes
WB: 1:1000-1:2000
Gene Name Synonym
Lupus La protein
Subcellular Location
Nucleus .
Protein Name
Lupus La protein
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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