Anti-p73 (phospho-Y99) TP73 Antibody
Boster Bio Anti-p73 (phospho-Y99) TP73 Antibody catalog # A00688Y99. Tested in IHC applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Tumor protein p73; p53-like transcription factor; p53-related protein; TP73; P73
Gene Name
TP73
UniProt
O15350
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthetic phosphopeptide derived from human p73 around the phosphorylation site of Tyrosine 99.
Clonality
Polyclonal
Tissue Specificity
Expressed in striatal neurons of patients with Huntington disease (at protein level) . Brain, kidney, placenta, colon, heart, liver, spleen, skeletal muscle, prostate, thymus and pancreas. Highly expressed in fetal tissue.
Applications
IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
69623 MW
Applications Notes
IHC: 1:50-1:200
Gene Name Synonym
Tumor protein p73
Subcellular Location
Nucleus
Protein Name
Tumor protein p73
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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