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Anti-p73 (phospho-Y99) TP73 Antibody

Boster Bio Anti-p73 (phospho-Y99) TP73 Antibody catalog # A00688Y99. Tested in IHC applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Tumor protein p73; p53-like transcription factor; p53-related protein; TP73; P73

Gene Name

TP73

UniProt

O15350

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthetic phosphopeptide derived from human p73 around the phosphorylation site of Tyrosine 99.

Clonality

Polyclonal

Tissue Specificity

Expressed in striatal neurons of patients with Huntington disease (at protein level) . Brain, kidney, placenta, colon, heart, liver, spleen, skeletal muscle, prostate, thymus and pancreas. Highly expressed in fetal tissue.

Applications

IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

69623 MW

Applications Notes

IHC: 1:50-1:200

Gene Name Synonym

Tumor protein p73

Subcellular Location

Nucleus

Protein Name

Tumor protein p73

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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