Anti-Copper-transporting ATPase 2 ATP7B Antibody
Boster Bio Anti-Copper-transporting ATPase 2 ATP7B Antibody catalog # A00686. Tested in WB applications. This antibody reacts with Mouse, Rat.
Product Specifications
Synonyms
Copper-transporting ATPase 2;3.6.3.54
Gene Name
ATP7B
UniProt
P35670
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein of human ATP7B (NP_001230111.1) .
Clonality
Polyclonal
Tissue Specificity
Most abundant in liver and kidney and also found in brain. Isoform 2 is expressed in brain but not in liver. The cleaved form WND/140 kDa is found in liver cell lines and other tissues.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/mL.
Form
Liquid
Function
Copper ion transmembrane transporter involved in the export of copper out of the cells. It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
157263 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
Copper-transporting ATPase 2
Subcellular Location
Golgi apparatus, trans-Golgi network membrane
Protein Name
Copper-transporting ATPase 2
Isotype
Rabbit IgG
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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