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Anti-Copper-transporting ATPase 2 ATP7B Antibody

Boster Bio Anti-Copper-transporting ATPase 2 ATP7B Antibody catalog # A00686. Tested in WB applications. This antibody reacts with Mouse, Rat.

Product Specifications

Synonyms

Copper-transporting ATPase 2;3.6.3.54

Gene Name

ATP7B

UniProt

P35670

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

Recombinant fusion protein of human ATP7B (NP_001230111.1) .

Clonality

Polyclonal

Tissue Specificity

Most abundant in liver and kidney and also found in brain. Isoform 2 is expressed in brain but not in liver. The cleaved form WND/140 kDa is found in liver cell lines and other tissues.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/mL.

Form

Liquid

Function

Copper ion transmembrane transporter involved in the export of copper out of the cells. It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

157263 MW

Applications Notes

WB: 1:500-1:2000

Gene Name Synonym

Copper-transporting ATPase 2

Subcellular Location

Golgi apparatus, trans-Golgi network membrane

Protein Name

Copper-transporting ATPase 2

Isotype

Rabbit IgG

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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