Anti-Major vault protein MVP Antibody
Boster Bio Anti-Major vault protein MVP Antibody catalog # A00642. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Major vault protein; MVP; Lung resistance-related protein; MVP; LRP
Gene Name
MVP
UniProt
Q14764
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein of human MVP (NP_005106.2) .
Clonality
Polyclonal
Tissue Specificity
Present in most normal tissues. Higher expression observed in epithelial cells with secretory and excretory functions, as well as in cells chronically exposed to xenobiotics, such as bronchial cells and cells lining the intestine. Overexpressed in many multidrug-resistant cancer cells.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Required for normal vault structure. Vaults are multi- subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo- cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
99327 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
Major vault protein
Subcellular Location
Cytoplasm
Protein Name
Major vault protein
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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