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Anti-Desmoplakin DSP Antibody

Boster Bio Anti-Desmoplakin DSP Antibody catalog # A00616. Tested in WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Desmoplakin; DP;250/210 kDa paraneoplastic pemphigus antigen; DSP

Gene Name

DSP

UniProt

P15924

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthetic peptide of human Desmoplakin (NP_004406.2) .

Clonality

Polyclonal

Tissue Specificity

Isoform DPI is apparently an obligate constituent of all desmosomes. Isoform DPII resides predominantly in tissues and cells of stratified origin.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin- plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

331774 MW

Applications Notes

WB: 1:500-1:2000

Gene Name Synonym

Desmoplakin

Subcellular Location

Cell junction, desmosome

Protein Name

Desmoplakin

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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