Anti-Histone deacetylase 6 HDAC6 Antibody
Boster Bio Anti-Histone deacetylase 6 HDAC6 Antibody catalog # A00595. Tested in WB, ICC/IF, IHC, IP applications. This antibody reacts with Human.
Product Specifications
Synonyms
Histone deacetylase 6; HD6;3.5.1.98; HDAC6; KIAA0901; JM21
Gene Name
HDAC6
UniProt
Q9UBN7
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein
Clonality
Polyclonal
Applications
WB, ICC, IF, IHC, IP
Purification
ProA affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity) . Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
131419 MW
Gene Name Synonym
Histone deacetylase 6
Subcellular Location
Nucleus. Cytoplasm. Perikaryon . Cell projection, dendrite . Cell projection, axon . It is mainly cytoplasmic, where it is associated with microtubules.
Protein Name
Histone deacetylase 6
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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