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Anti-SAMHD1 Antibody

Boster Bio Anti-SAMHD1 Antibody (Catalog# A00592) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Synonyms

Deoxynucleoside triphosphate triphosphohydrolase SAMHD1; dNTPase;3.1.5.-; Dendritic cell-derived IFNG-induced protein; DCIP; Monocyte protein 5; MOP-5; SAM domain and HD domain-containing protein 1; SAMHD1; MOP5

Gene Name

SAMHD1

UniProt

Q9Y3Z3

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant SAMHD1 protein (amino acids 380-520)

Clonality

Polyclonal

Tissue Specificity

Expressed in heart, skeletal muscle, spleen, liver, small intestine, placenta, lung and peripheral blood leukocytes. No expression is seen in brain and thymus.

Applications

WB

Field of Research

Host-Virus Interaction, Interspecies Interaction, Microbiology

Purification

Protein A Chromatography

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling. .

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Observed Molecular Weight

72201 MW

Applications Notes

Western blot: 2-4 μg/ml

Gene Name Synonym

Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

Subcellular Location

Nucleus.

Protein Name

Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

Isotype

Rabbit IgG

Contents

100 μ g in 200 μ l PBS containing 0.05% BSA and 0.05% sodium azide.

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