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Anti-Phospho-CREB (S133) Antibody

Boster Bio Anti-Phospho-CREB (S133) Antibody (Catalog # A00577) . Tested in IHC-P-Leica, IF, WB application (s) . This antibody reacts with Human.

Product Specifications

Background

CREB is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, (CRE), a sequence present in many viral and cellular promoters. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway.

Synonyms

Cyclic AMP-responsive element-binding protein 1, CREB-1, cAMP-responsive element-binding protein 1, CREB1

Gene Name

CREB1

UniProt

P16220

Host

Rabbit

Reactivity

Human

Immunogen

This CREB Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S133 of human CREB.

Clonality

Polyclonal

Applications

IHC-P-Leica, IF, WB

Field of Research

Cancer, Cell Biology, Immunology, Microbiology, Neuroscience, Signal Transduction, Viral process, Host-Virus Interaction, Apoptosis

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

14536081

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

35136 Da

Subcellular Location

Nucleus {ECO:0000255|PROSITE-ProRule:PRU00312, ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:12552083}

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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