Anti-Fibronectin 1 FN1 Antibody
Boster Bio Anti-Fibronectin 1 FN1 Antibody catalog # A00564. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Fibronectin; FN; Cold-insoluble globulin; CIG; Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3; FN1; FN
Gene Name
FN1
UniProt
P02751
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human FN1
Clonality
Polyclonal
Tissue Specificity
Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine.
Applications
WB, IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
262625 MW
Gene Name Synonym
Fibronectin
Subcellular Location
Secreted, extracellular space, extracellular matrix.
Protein Name
Fibronectin
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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