Anti-SRF (phospho-S103) Antibody
Boster Bio Anti-SRF (phospho-S103) Antibody catalog # A00557S103. Tested in WB, IHC applications. This antibody reacts with Human.
Product Specifications
Synonyms
Serum response factor; SRF; SRF
Gene Name
SRF
UniProt
P11831
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic phosphopeptide derived from human SRF around the phosphorylation site of Serine 103.
Clonality
Polyclonal
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS) . Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics. Required for cardiac differentiation and maturation.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
51593 MW
Gene Name Synonym
Serum response factor
Subcellular Location
Nucleus
Protein Name
Serum response factor
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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