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Anti-ERBB3 (phospho-Y1328) Antibody

Boster Bio Anti-ERBB3 (phospho-Y1328) Antibody catalog # A00539Y1328. Tested in WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Receptor tyrosine-protein kinase erbB-3;2.7.10.1; Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3; ERBB3; HER3

Gene Name

ERBB3

UniProt

P21860

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthetic peptide corresponding to residues in Human ERBB3 around the phosphorylation site of Y1328.

Clonality

Polyclonal

Tissue Specificity

Epithelial tissues and brain.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778) . May also be activated by CSPG5 (PubMed:15358134) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

148098 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Receptor tyrosine-protein kinase erbB-3

Subcellular Location

Isoform 1: Cell membrane; Single-pass type I membrane protein.

Protein Name

Receptor tyrosine-protein kinase erbB-3

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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