Anti-Fibroblast growth factor 23 FGF23 Antibody
Boster Bio Anti-Fibroblast growth factor 23 FGF23 Antibody catalog # A00478. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Fibroblast growth factor 23; FGF-23; Phosphatonin; Tumor-derived hypophosphatemia-inducing factor; Fibroblast growth factor 23 N-terminal peptide; Fibroblast growth factor 23 C-terminal peptide; FGF23; HYPF; UNQ3027/PRO9828
Gene Name
FGF23
UniProt
Q9GZV9
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant full length Human FGF23.
Clonality
Polyclonal
Tissue Specificity
Expressed in osteogenic cells particularly during phases of active bone remodeling. In adult trabecular bone, expressed in osteocytes and flattened bone-lining cells (inactive osteoblasts) .
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity) . Acts directly on the parathyroid to decrease PTH secretion (By similarity) . Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
27954 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
Fibroblast growth factor 23
Subcellular Location
Secreted
Protein Name
Fibroblast growth factor 23
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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