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Anti-Cytochrome P450 2C9 CYP2C9 Antibody

Boster Bio Anti-Cytochrome P450 2C9 CYP2C9 Antibody catalog # A00465. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Cytochrome P450 2C9;1.14.14.-

Gene Name

CYP2C9

UniProt

P11712

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human CYP2C9.

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics (PubMed:25994031) . This enzyme contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S-warfarin, diclofenac, phenytoin, tolbutamide and losartan (PubMed:25994031) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

55628 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Cytochrome P450 2C9

Subcellular Location

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane

Protein Name

Cytochrome P450 2C9

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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