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Anti-ITRAF TANK Antibody

Boster Bio Anti-ITRAF TANK Antibody (Catalog# A00445) . Tested in IP, IHC, WB application (s) . This antibody reacts with Human.

Product Specifications

Synonyms

TRAF family member-associated NF-kappa-B activator; TRAF-interacting protein; I-TRAF; TANK; ITRAF, TRAF2

Gene Name

TANK

UniProt

Q92844

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide of human ITRAF (amino acids 346-367 DPSDAPFPSLDSPGKAIRGPQQ)

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

IP, IHC, WB

Field of Research

Growth Factors/Hormones, Immunology, Innate Immunity, NFKB Pathway, Nuclear Signaling, Signal Transduction, Signaling Pathway, TLR Signaling

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Adapter protein involved in I-kappa-B-kinase (IKK) regulation which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity. Acts as a regulator of TRAF function by maintaining them in a latent state. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May control negatively TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2. .

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Observed Molecular Weight

47816 MW

Gene Name Synonym

TRAF family member-associated NF-kappa-B activator

Subcellular Location

Cytoplasm.

Protein Name

TRAF family member-associated NF-kappa-B activator

Isotype

Rabbit IgG

Contents

50 μ l sera

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