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Anti-IGFBP-3 (Phospho-Ser183) Antibody

Boster Bio Anti-IGFBP-3 (Phospho-Ser183) Antibody catalog # A00435S183. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Insulin-like growth factor-binding protein 3; IBP-3; IGF-binding protein 3; IGFBP-3; IGFBP3; IBP3

Gene Name

IGFBP3

UniProt

P17936

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic phosphopeptide derived from human IGFBP-3 around the phosphorylation site of Serine 183

Clonality

Polyclonal

Tissue Specificity

Expressed by most tissues. Present in plasma.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

31674 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Insulin-like growth factor-binding protein 3

Subcellular Location

Secreted

Protein Name

Insulin-like growth factor-binding protein 3

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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