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Anti-ETV6 Antibody (N-term)

Boster Bio Anti-ETV6 Antibody (N-term) (Catalog # A00361-2) . Tested in WB, Flow Cytometry, IHC-P application (s) . This antibody reacts with Human.

Product Specifications

Background

ETV6 is an ETS family transcription factor. This protein contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain.

Synonyms

Transcription factor ETV6, ETS translocation variant 6, ETS-related protein Tel1, Tel, ETV6, TEL, TEL1

Gene Name

ETV6

UniProt

P41212

Host

Rabbit

Reactivity

Human

Immunogen

This ETV6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-111 amino acids from the N-terminal region of human ETV6.

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

WB, Flow Cytometry, IHC-P

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Transcriptional repressor; binds to the DNA sequence 5'- CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

53000 Da

Subcellular Location

Nucleus.

Prediction Reactivity

Bovine, Mouse

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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