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Anti-CEA Antibody (Center)

Boster Bio Anti-CEA Antibody (Center) (Catalog # A00356-1) . Tested in IHC-P-Leica, Flow Cytometry, WB application (s) . This antibody reacts with Human.

Product Specifications

Background

CEA is a cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. It is a receptor for E.coli Dr adhesins.

Synonyms

Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen, CEA, Meconium antigen 100, CD66e, CEACAM5, CEA

Gene Name

CEACAM5

UniProt

P06731

Host

Rabbit

Reactivity

Human

Immunogen

This CEA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-429 amino acids from the Central region of human CEA.

Clonality

Polyclonal

Tissue Specificity

Expressed in columnar epithelial and goblet cells of the colon (at protein level) (PubMed:10436421) . Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.

Applications

IHC-P-Leica, Flow Cytometry, WB

Field of Research

Cancer, Immunology, Microbiology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

28033081091005010864933280330810910050

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

76796 Da

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane. Cell surface Note=Localized to the apical glycocalyx surface

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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