Anti-Insulin-like growth factor II IGF2 Antibody
Boster Bio Anti-Insulin-like growth factor II IGF2 Antibody catalog # A00335. Tested in WB, ICC/IF, IHC applications. This antibody reacts with Human.
Product Specifications
Synonyms
Insulin-like growth factor II; IGF-II; Somatomedin-A; T3M-11-derived growth factor; Insulin-like growth factor II; Insulin-like growth factor II Ala-25 Del; Preptin; IGF2; PP1446
Gene Name
IGF2
UniProt
P01344
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein
Clonality
Polyclonal
Tissue Specificity
Expressed in heart, placenta, lung, liver, muscle, kidney, tongue, limb, eye and pancreas.
Applications
WB, ICC, IF, IHC
Purification
ProA affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation (By similarity) . In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver (Probable) . Acts as a ligand for integrin which is required for IGF2 signaling (PubMed:28873464) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
20140 MW
Gene Name Synonym
Insulin-like growth factor II
Subcellular Location
Secreted
Protein Name
Insulin-like growth factor II
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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