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Anti-JAK1 (phospho-Y1022) Antibody

Boster Bio Anti-JAK1 (phospho-Y1022) Antibody catalog # A00330Y1022. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Tyrosine-protein kinase JAK1;2.7.10.2

Gene Name

JAK1

UniProt

P23458

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic phosphopeptide derived from human JAK1 around the phosphorylation site of Tyrosine 1022.

Clonality

Polyclonal

Tissue Specificity

Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway (PubMed:7615558) . Kinase partner for the interleukin (IL) -2 receptor (PubMed:11909529) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

133277 MW

Gene Name Synonym

Tyrosine-protein kinase JAK1

Subcellular Location

Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated.

Protein Name

Tyrosine-protein kinase JAK1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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