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Anti-Paired box protein Pax-6 PAX6 Antibody

Boster Bio Anti-Paired box protein Pax-6 PAX6 Antibody catalog # A00273. Tested in WB, ICC/IF, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Paired box protein Pax-6; Aniridia type II protein; Oculorhombin; PAX6; AN2

Gene Name

PAX6

UniProt

P26367

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein

Clonality

Polyclonal

Tissue Specificity

Fetal eye, brain, spinal cord and olfactory epithelium. Isoform 5a is less abundant than the PAX6 shorter form.

Applications

WB, ICC, IF, IHC

Purification

ProA affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity) . Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity) . Isoform 5a appears to function as a molecular switch that specifies target genes. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

46683 MW

Gene Name Synonym

Paired box protein Pax-6

Subcellular Location

Nucleus.

Protein Name

Paired box protein Pax-6

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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