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Anti-IRS-1 (phospho-S307) Antibody

Boster Bio Anti-IRS-1 (phospho-S307) Antibody catalog # A00268S307. Tested in IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Insulin receptor substrate 1; IRS-1; IRS1

Gene Name

IRS1

UniProt

P35568

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic phosphopeptide derived from human IRS-1 around the phosphorylation site of Serine 307.

Clonality

Polyclonal

Applications

IHC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

131591 MW

Gene Name Synonym

Insulin receptor substrate 1

Protein Name

Insulin receptor substrate 1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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