Anti-FOXO3A/FOXO3 Antibody
Boster Bio Anti-FOXO3A/FOXO3 Antibody catalog # A00252-3. Tested in WB, IHC, ICC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
Forkhead box O3, also known as FKHRL1 or FOXO3a, is a human protein encoded by the FOXO3 gene. FOXO3 belongs to the O subclass of the forkhead family of transcription factors which are characterized by a distinct fork head DNA-binding domain. It is mapped to 6q21. This protein likely functions as a trigger for apoptosis through upregulation of genes necessary for cell death, such as Bim and PUMA, or downregulation of anti-apoptotic proteins such as FLIP. In mammals FOXO3 regulates the resistance of cells to stress by inducing DNA repair and thereby may also affect organismal life span. In addition, it is thought that FOXO3 is also involved in protection from oxidative stress by upregulating antioxidants such as catalase and MnSOD.
Gene Name
FOXO3
UniProt
O43524
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human FOXO3A/FOXO3 recombinant protein (Position: R323-W670) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A00252-3
Product MSDS
https://www.bosterbio.com/msds?sku=A00252-3
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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