Anti-Histone H2A.X/H2AFX Antibody
Boster Bio Anti-Histone H2A.X/H2AFX Antibody catalog # A00241-4. Tested in WB, IHC, ICC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat, Monkey.
Product Specifications
Background
H2A histone family member X (usually abbreviated as H2AX) is a type of histone protein from the H2A family encoded by the H2AFX gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Gene Name
H2AX
UniProt
P16104
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat
Immunogen
E.coli-derived human Histone H2A.X/H2AFX recombinant protein (Position: S2-S140) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF, Flow Cytometry, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Applications Notes
6
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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