Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-MAPK14 Antibody (Y323)

Boster Bio Anti-MAPK14 Antibody (Y323) (Catalog # A00176-1) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.

Synonyms

Mitogen-activated protein kinase 14, MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAP kinase MXI2, MAX-interacting protein 2, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Stress-activated protein kinase 2a, SAPK2a, MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A

Gene Name

MAPK14

UniProt

Q16539

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This MAPK14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-330 amino acids from human MAPK14.

Clonality

Polyclonal

Tissue Specificity

Brain, heart, placenta, pancreas and skeletal muscle. Expressed to a lesser extent in lung, liver and kidney

Applications

WB, Flow Cytometry

Field of Research

T Cells, TLR Signaling, Signal Transduction, Neuroscience, Immunology, Cell Biology, Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

968751097926779687510979267711154262107478971700304519893488169327402018867394307219858528103301431133398620932473109438421590557235857590

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

41293 Da

Subcellular Location

Cytoplasm. Nucleus

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBD1 (NM_015846) Human Untagged Clone
SC314167 10 µg

MBD1 (NM_015846) Human Untagged Clone

Ask
View Details
SLC9A1 Knockout SK-MEL-28 Cell Line
ARG44118 1 Million

SLC9A1 Knockout SK-MEL-28 Cell Line

Ask
View Details
JAK/HDAC-IN-1 100mg
A13362-100 100 mg

JAK/HDAC-IN-1 100mg

Ask
View Details
TSC22D4 (TSC22 Domain Family, Member 4, THG-1, THG1) (Biotin)
MBS6171063-01 0.1 mL

TSC22D4 (TSC22 Domain Family, Member 4, THG-1, THG1) (Biotin)

Ask
View Details
TSC22D4 (TSC22 Domain Family, Member 4, THG-1, THG1) (Biotin)
MBS6171063-02 5x 0.1 mL

TSC22D4 (TSC22 Domain Family, Member 4, THG-1, THG1) (Biotin)

Ask
View Details
KLRC1 Antibody
A72974-50UL 50 μL

KLRC1 Antibody

Ask
View Details