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Anti-C-C chemokine receptor type 2 CCR2 Antibody

CCR2 Antibody

Product Specifications

Synonyms

C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2; CCR-2; CCR2; Monocyte chemoattractant protein 1 receptor; MCP-1-R; CD192; CCR2; CMKBR2

Gene Name

CCR2

UniProt

P41597

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein

Clonality

Polyclonal

Tissue Specificity

Expressed by monocytes and IL2-activated NK cells.

Applications

WB, IHC, IP, Flow Cytometry

Purification

ProA affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

Receptor for the CCL2, CCL7 and CCL13 chemokines (PubMed:23408426) . Receptor for the beta-defensin DEFB106A/DEFB106B (PubMed:23938203) . Transduces a signal by increasing intracellular calcium ion levels (By similarity) . Upon CCL2 ligation, mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (Probable) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

41915 MW

Gene Name Synonym

C-C chemokine receptor type 2

Subcellular Location

Cell membrane

Protein Name

C-C chemokine receptor type 2

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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