Anti-C-C chemokine receptor type 2 CCR2 Antibody
CCR2 Antibody
Product Specifications
Synonyms
C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2; CCR-2; CCR2; Monocyte chemoattractant protein 1 receptor; MCP-1-R; CD192; CCR2; CMKBR2
Gene Name
CCR2
UniProt
P41597
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein
Clonality
Polyclonal
Tissue Specificity
Expressed by monocytes and IL2-activated NK cells.
Applications
WB, IHC, IP, Flow Cytometry
Purification
ProA affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Receptor for the CCL2, CCL7 and CCL13 chemokines (PubMed:23408426) . Receptor for the beta-defensin DEFB106A/DEFB106B (PubMed:23938203) . Transduces a signal by increasing intracellular calcium ion levels (By similarity) . Upon CCL2 ligation, mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (Probable) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
41915 MW
Gene Name Synonym
C-C chemokine receptor type 2
Subcellular Location
Cell membrane
Protein Name
C-C chemokine receptor type 2
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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