Anti-CD28 Antibody
Boster Bio Anti-CD28 Antibody (Catalog # A00065) . Tested in ELISA, WB, IHC, IF applications. This antibody reacts with Human.
Product Specifications
Synonyms
CD28 Molecule, CD28 Antigen, Tp44, T-Cell-Specific Surface Glycoprotein CD28, T-Cell-Specific Surface Glycoprotein, CD28 Antigen (Tp44)
Gene Name
CD28
UniProt
P10747
Host
Rabbit
Reactivity
Human
Immunogen
CD28 antibody was raised against a peptide corresponding to 18 amino acids near the carboxy terminus of human CD28. The immunogen is located within the last 50 amino acids of CD28.
Clonality
Polyclonal
Tissue Specificity
Expressed in T-cells and plasma cells, but not in less mature B-cells.
Applications
ELISA, WB, IHC, IF
Field of Research
Immunology
Purification
CD28 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Form
Liquid
Function
Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation (PubMed:8617933) . Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (PubMed:15067037) .
Storage Conditions
CD28 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Observed Molecular Weight
25066 MW
Gene Name Synonym
CD28 molecule
Subcellular Location
Membrane; Single-pass type I membrane protein.
Prediction Reactivity
Rabbit, Bovine, Cat, Rat, Mouse
Protein Name
CD28 molecule
Isotype
IgG
Contents
CD28 Antibody is supplied in PBS containing 0.02% sodium azide.
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