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Anti-EZH2 Antibody

Boster Bio Anti-EZH2 Antibody (Catalog # A00050-3) . Tested in WB, IHC-P, IF, Flow Cytometry application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Background

EZH2 is a protein that transfers sulfate to the C-4 hydroxyl of beta-1,4-linked GalNAc flanked by GlcUA residues in chondroitin.

Synonyms

Histone-lysine N-methyltransferase EZH2, ENX-1, Enhancer of zeste homolog 2, Lysine N-methyltransferase 6, EZH2, KMT6

Gene Name

EZH2

UniProt

Q15910

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This EZH2 antibody is generated from rabbits immunized with a recombinant fragment (N-term) protein from human EZH2.

Clonality

Polyclonal

Tissue Specificity

In the ovary, expressed in primordial follicles and oocytes and also in external follicle cells (at protein level) (PubMed:31451685) . Expressed in many tissues (PubMed:14532106) Overexpressed in numerous tumor types including carcinomas of the breast, colon, larynx, lymphoma and testis (PubMed:14532106)

Applications

WB, IHC-P, IF, Flow Cytometry

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

2232359930923826

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

85363 Da

Subcellular Location

Nucleus. Note=Localizes to the inactive X chromosome in trophoblast stem cells. {ECO:0000250|UniProtKB:Q61188}

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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