Anti-CD152 CTLA4 Antibody
Boster Bio Anti-CD152 CTLA4 Antibody catalog # A00020. Tested in IHC, IF, ELISA applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD152; CTLA4; CD152
Gene Name
CTLA4
UniProt
P16410
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthetic peptide from human protein at AA range: 41-90
Clonality
Polyclonal
Tissue Specificity
Widely expressed with highest levels in lymphoid tissues. Detected in activated T-cells where expression levels are 30- to 50-fold less than CD28, the stimulatory coreceptor, on the cell surface following activation. .
Applications
IHC, IF, ELISA
Purification
Immunogen affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
24656 MW
Gene Name Synonym
Cytotoxic T-lymphocyte protein 4
Subcellular Location
Cell membrane ; Single-pass type I membrane protein . Exists primarily an intracellular antigen whose surface expression is tightly regulated by restricted trafficking to the cell surface and rapid internalisation; .
Isotype
IgG
Contents
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
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